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New Blood Test for Down Syndrome
October 06, 2008
HHMI researchers devise prenatal blood test that accurately detects Down syndrome and two other serious chromosomal defects. More
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New Research Shows MicroRNAs Emerged Early in Evolution
October 01, 2008
HHMI researchers have found microRNAs in animal species whose last common ancestors were present on Earth about 1 billion years ago. More
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New Pig Model Could Improve Understanding of Cystic Fibrosis
September 26, 2008
HHMI researchers have developed a new model of cystic fibrosis in pigs that more accurately mimics features of the disease. More
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Elusive Chloride Channel Corralled in Salamander Eggs
September 19, 2008
Researchers have identified a gene from a new family of ion channels that control the flow of chloride ions into cells, helping to regulate smell and taste sensing, smooth muscle contraction, and fluid secretion in glands and airways. More
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Nervous System Rallies Immune System Forces Against Invading Pathogens
September 18, 2008
Researchers have discovered a communications "hot line" that lets a worm's nervous system dial the immune system to help coordinate the response to infectious pathogens. More
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Listeria Bacteria’s Two-Pronged Attack Puts Pregnancies at Risk
September 17, 2008
For the first time, researchers have learned how the dangerous foodborne pathogen Listeria crosses the placenta from mother to baby. More
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Seeing the Shape of Gene Silencing
September 14, 2008
Researchers have devised clever new techniques to mimic the chemical marks on tightly wound DNA-protein complexes that silence gene expression. The scientists have used these complexes to visualize gene silencing in its natural context for the first time. More
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Cholesterol and Malaria May Use Same Doorway to Liver Cells
September 10, 2008
Current anti-malaria drugs target the parasite that causes the disease, but those are becoming less effective due to increasing drug resistance. Now, Howard Hughes Medical Institute researchers report that they may be able to fight malaria by targeting human liver cells instead of parasites. More
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Change in Single Gene Causes Degenerative Brain Disease in Mice
September 10, 2008
Change in Single Gene Causes Degenerative Brain Disease in Mice
Mice whose brains receive half the dose of a critical growth-regulating gene exhibit the altered behaviors and nerve cell tangles common in people with Alzheimer's disease or dementia, according to a new report by Howard Hughes Medical Institute (HHMI) scientists. More
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Surprise Finding Identifies Ways to Fight African Sleeping Sickness
September 08, 2008
A drug currently used to help transplant patients may unexpectedly lead to new cures for African sleeping sickness. More
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